I, a non-medical professional, have been reading for 4 1/2 years about Multiple Sclerosis (MS). What I find most disturbing is not the fact that a cure has not been found. It is ALL the holes in the current theory that MS is secondary to our own immune system becoming overactive due to some 'unknown outside viral/bacteria agent.' Thus it is attacking itself and being classified as an autoimmune disease.
Let us start with a Mayo 2000, the National Institute of Arthritis Health (NIAH) 2004 study and 2005 NIH government study that all conclude that Multiple Sclerosis (MS) & Rheumatoid Arthritis (RA) are both 'aged' or weakened immune systems. I find these organizations to be creditable and have no reason to present false data. This data would seem to disprove the current theory. This added to the fact that after decades of research NO one 'viral or bacteria agent' has been found in the majority of MS patients, let alone all of them. In this theory, there is no reason as to why some people have the remitting form of the disease, and others the progressive form thus the continuous deterioration of the symptomatology.
For these reasons, I started to look for a different theory, which has led me to a new theory. My THEORY of these diseases are that malabsorption/ metabolism problems most probably due to hormone imbalance/resistance and liver malfunction leads to cells not getting proper nutrition. Thus the cell is unable to replicate and repair themselves and you have tissue degrade. In the old theory, a cold comes into your body and your 'aged' immune system is overactive and attacks itself. In my theory, a cold comes in and as your immune system is attacking the outside agent, damage occurs to already compromised tissues. Once this damage exists, your body is unable to repair the damage. If the deficiency were mild, the disease would probably progress at a much slower rate. If you have an almost complete block of absorption of a vitamin at the cell level the disease would progress rapidly.
How does this fit in with previous research? Vitamin D3 has been shown to reduce the incidence of MS by 41% (see Vitamin D3 link). This is a better rate than copaxone or interferions. High homocysteine levels, correlate to low B Vitamins, have been associated with low cognitive scores in SPMS and PPMS(see B link). Steriods help most that have MS, studies show that estriol and testosterone help SOME with MS, and vitamin D3 which is turned into a secosteriod help others who suffer from MS where the myelin is thinning and is damaged. What do these things have in common? Fat is what they have in common. Hormones like estriol are made of fat. Steriods & secosteriods made of fat. Even the thinning myelin is made of fat and B vitamins are used to process hormones like estriol in the liver. Maybe a few subclasses of MS are having problems metabolizing fat in the body.
Lets look at some Supporting Data